STKE: Painful Inflammatory Responses

Acute painful stress and inflammatory mediator production.

BACKGROUND Proinflammatory pathways may be activated under conditions of painful stress, which is hypothesized to worsen the experience of pain and place medically vulnerable populations at risk for increased morbidity. OBJECTIVES To evaluate the effects of pain and subjective pain-related stress on proinflammatory activity. METHODS A total of 19 healthy control subjects underwent a single ...

The responses to painful stimuli of patients with severe chronic painful conditions.

In the study of patients who have severe and prolonged, chronic, painful conditions, it is a clinical fact that some will react more profoundly than others to what are apparently similar conditions. It is also obvious clinically that pain is an extreme fearand anxiety-provoking stimulus. Furthermore, the diagnosis of "functional pain," or of a "functional element" in pain, is one frequently att...

Keratinocyte Inflammatory Responses

Lung inflammatory responses.

Inflammation is an important manifestation of respiratory disease in domestic animals. The respiratory system is mucosal in nature and has specific defense mechanisms used to control invasion by microbes and environmental elements. Inflammation can be beneficial or detrimental to the host. This article broadly discusses the primary mediators and mechanisms of inflammation within the respiratory...

Inflammatory Responses to Pneumovirus